The Cannes Film Festival opens Wednesday with a movie called "Blindness" about a city where everyone except for one woman goes blind.

Based on the novel by Nobel Prize-winning author Jose Saramago, the film version is directed by Fernando Meirelles ("City of God," "The Constant Gardener") and stars Julianne Moore, Mark Ruffalo and Gael Garcia Bernal.

In the film, as the blindness epidemic spreads, the people that can see begin to prey on the sightless.

Check out an L.A. Times "first look" and watch a clip from the film.

The book came out in 1998 and the author turned down multiple offers to adapt it before granting Meirelles permission.

According to IMDB, the film is scheduled for U.S. realease in September.

Read more about Cannes here.